Type I Collagen Nerve Conduits for Median Nerve Repairs in the Forearm

Dienstknecht, Thomas and Klein, Silvan and Vykoukal, Jody and Gehmert, Sebastian and Koller, Michael and Gosau, Martin and Prantl, Lukas (2013) Type I Collagen Nerve Conduits for Median Nerve Repairs in the Forearm. JOURNAL OF HAND SURGERY-AMERICAN VOLUME, 38A (6). pp. 1119-1124. ISSN 0363-5023,

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Abstract

Purpose To evaluate patients with median nerve damage in the distal forearm treated with type 1 collagen nerve conduits. Methods Nine patients with damage to the median nerve in the distal forearm underwent treatment with a type 1 collagen nerve conduit. The nerve gaps ranged between 1 and 2 cm. An independent observer reexamined patients after treatment at a minimal follow-up of 14 months and a mean follow-up of 21 months. Residual pain was evaluated using a visual analog scale. Functional outcome was quantified by assessing static 2-point discrimination, nerve conduction velocity relative to the uninjured limb, and Disabilities of the Arm, Shoulder, and Hand outcome measure scoring. We also recorded quality of life measures including patients' perceived satisfaction with the results and return to work latency. Results We observed no implant-related complications. Of 9 patients, 7 were free of pain, and the mean visual analog scale was 0.6. The mean Disabilities of the Arm, Shoulder, and Hand score was 6. The static 2-point discrimination was less than 6 mm in 3 patients, between 6 and 10 mm in 4 patients, and over 10 mm in 2 patients. Six patients reached a status of M4 or higher. Eight patients were satisfied with the procedure and would undergo surgery again. Conclusions This study indicates that purified type 1 bovine collagen conduits are a practical and efficacious method for the repair of median nerves in the distal forearm. (Copyright (C) 2013 by the American Society for Surgery of the Hand. All rights reserved.)

Item Type: Article
Uncontrolled Keywords: CLINICAL-EXPERIENCE; POLYGLYCOLIC ACID; UPPER EXTREMITY; RECONSTRUCTION; REGENERATION; MANAGEMENT; ALLOGRAFTS; GAP; TRANSFERS; INJURIES; Collagen; large-diameter nerve; nerve conduit; nerve reconstruction; peripheral nerve repair
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie
Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien
Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Apr 2020 08:10
Last Modified: 08 Apr 2020 08:10
URI: https://pred.uni-regensburg.de/id/eprint/16567

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