Intraoperative chemotherapy after radical pleurectomy or extrapleural pneumonectomy

Ried, M. and Hofmann, H. -S. (2013) Intraoperative chemotherapy after radical pleurectomy or extrapleural pneumonectomy. CHIRURG, 84 (6). pp. 492-496. ISSN 0009-4722,

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Abstract

Trimodality treatment including induction and/or adjuvant chemotherapy, surgical resection and in some cases radiotherapy offers a curative intention in selected patients with pleural malignancies (malignant pleural mesothelioma, thymoma with pleural spread). Nevertheless, locoregional tumor recurrence mainly limits the outcome and the quality of life. A few years ago an additional intraoperative chemotherapy perfusion was developed in order to improve local tumor control and prognosis after surgical resection in a multimodality treatment setting. Cytoreductive surgery with the purpose of a macroscopic complete resection could be achieved by radical pleurectomy or extrapleural pneumonectomy. The concept, techniques and perioperative management of this additional treatment option are presented along with a detailed review of the recent literature.

Item Type: Article
Uncontrolled Keywords: MALIGNANT PLEURAL MESOTHELIOMA; HYPERTHERMIC INTRATHORACIC CHEMOTHERAPY; CYTOREDUCTIVE SURGERY; PHASE-II; INTRAPLEURAL CISPLATIN; PLEURECTOMY/DECORTICATION; PERFUSION; MANAGEMENT; RESECTION; CYTOPROTECTION; Intraoperative chemotherapy; Radical pleurectomy; Extrapleural pneumonectomy; Malignant pleural mesothelioma; Thymoma
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Abteilung für Thoraxchirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Apr 2020 08:36
Last Modified: 08 Apr 2020 08:36
URI: https://pred.uni-regensburg.de/id/eprint/16572

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