Salas-Gonzalez, D. and Gorriz, J. M. and Ramirez, J. and Schloegl, M. and Lang, E. W. and Ortiz, A. (2013) Parameterization of the distribution of white and grey matter in MRI using the alpha-stable distribution. COMPUTERS IN BIOLOGY AND MEDICINE, 43 (5). pp. 559-567. ISSN 0010-4825, 1879-0534
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This work presents a study of the distribution of the grey matter (GM) and white matter (WM) in brain magnetic resonance imaging (MRI). The distribution of GM and WM is characterized using a mixture of alpha-stable distributions. A Bayesian alpha-stable mixture model for histogram data is presented and unknown parameters are sampled using the Metropolis-Hastings algorithm. The proposed methodology is tested in 18 real images from the MRI brain segmentation repository. The GM and WM distributions are accurately estimated. The alpha-stable distribution mixture model presented in this paper can be used as previous step in more complex MRI segmentation procedures using spatial information. Furthermore, due to the fact that the alpha-stable distribution is a generalization of the Gaussian distribution, the proposed methodology can be applied instead of the Gaussian mixture model, which is widely used in segmentation of brain MRI in the literature. (C) 2013 Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MEDICAL IMAGE SEGMENTATION; BRAIN IMAGES; TISSUE CLASSIFICATION; MIXTURE-MODELS; FINITE MIXTURE; MRI segmentation; Mixture models; alpha-Stable distribution |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Elmar Lang |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Apr 2020 05:04 |
| Last Modified: | 09 Apr 2020 05:04 |
| URI: | https://pred.uni-regensburg.de/id/eprint/16625 |
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