MR Enterography Sequence Evaluation for Patients with Crohn's Disease

Schleder, S. and Dendl, L. -M. and Pawlik, M. and Friedrich, C. and Ott, C. and Agha, A. and Wiggermann, P. and Stroszczynski, C. and Schreyer, A. G. (2013) MR Enterography Sequence Evaluation for Patients with Crohn's Disease. ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN, 185 (5). pp. 440-445. ISSN 1438-9029,

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Abstract

Purpose: To evaluate a routine MR enterography (MRE) protocol for patients with Crohn's disease (CD) in order to assess and rank the subjectively most important sequences regarding diagnostic decisions. Materials and Methods: We prospectively examined 84 patients (42 male) with known CD using a coronal T2 / T1-weighted balanced SSFP (TrueFISP), axial T2-weighted single shot TSE (HASTE) as well as an axial T1-weighted gradient-echo sequence (2D-FLASH) before intravenous contrast application and a 2D-FLASH sequence with axial and coronal orientation after intravenous contrast application. 4 experienced radiologists subjectively evaluated the sequences independently using a scale between 1 and 5 (1 = excellent; 5 = non-diagnostic) regarding their diagnostic significance for a final radiologic decision. The ranking of the different sequences was statistically tested by the Friedman analysis. Results: The following ranking was found: HASTE sequences were ranked prior to contrast-enhanced axial gradient-echo (2D-FLASH). The third to fifth ranking was TrueFISP, the axial contrast-enhanced 2D-FLASH and the 2D-FLASH without contrast, respectively. Differences between the first and second rank were significant (p < 0.05), and all other differences were highly significant (p < 0.01). Conclusion: The stable and fast T2-weighted MR sequences without intravenous contrast represented by axial HASTE and coronal TrueFISP were ranked as number 1 and 3. The examination protocol should be completed by a coronal T1-weighted gradient-echo-sequence after contrast injection, which can be supplemented by an axial acquisition. The T1-weighted gradient-echo sequence without contrast could be omitted.

Item Type: Article
Uncontrolled Keywords: INFLAMMATORY-BOWEL-DISEASE; CONVENTIONAL ENTEROCLYSIS; ORAL CONTRAST; ILEOCOLONOSCOPY; COLONOGRAPHY; DIAGNOSIS; CT; abdomen; MR imaging; efficacy studies
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Medicine > Lehrstuhl für Innere Medizin I
Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 09 Apr 2020 07:32
Last Modified: 09 Apr 2020 07:32
URI: https://pred.uni-regensburg.de/id/eprint/16693

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