Kohl, E. and Karrer, S. (2013) New developments in photodynamic therapy. HAUTARZT, 64 (5). pp. 363-369. ISSN 0017-8470,
Full text not available from this repository. (Request a copy)Abstract
We review new developments in recent years in photodynamic therapy. Since 2009 two new photosensitizers, a self-adhesive 5-aminolevulinic acid (ALA) patch and a nanoemulsion formulation of 5-aminolevulinic acid have been approved for the treatment of actinic keratoses. Pretreatment with ablative fractional lasers enhances penetration of the photosensitizer and enables intensified PDT in acral lesions and in field-cancerized skin. Several clinical trials have demonstrated the skin-rejuvenating effects of photodynamic therapy, while the underlying mechanisms of action have been clarified. The efficacy of photodynamic therapy has been shown in the treatment and prophylaxis of actinic keratoses in organ transplant recipients at high risk for developing skin cancer. We also summarize the results of available studies on daylight-mediated photodynamic therapy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ORGAN-TRANSPLANT RECIPIENTS; TOPICAL METHYL AMINOLEVULINATE; INTENSE PULSED-LIGHT; RANDOMIZED-CONTROLLED-TRIAL; SQUAMOUS-CELL CARCINOMA; ACTINIC KERATOSIS; 5-AMINOLEVULINIC ACID; IMIQUIMOD 5-PERCENT; DAYLIGHT EXPOSURE; CLINICAL-TRIAL; Aminolevulinic acid; Methylaminolevulinate; Organ transplantation; Daylight PDT; Photorejuvenation |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Apr 2020 11:58 |
| Last Modified: | 09 Apr 2020 11:58 |
| URI: | https://pred.uni-regensburg.de/id/eprint/16713 |
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