Hamperl, Stephan and Wittner, Manuel and Babl, Virginia and Perez-Fernandez, Jorge and Tschochner, Herbert and Griesenbeck, Joachim (2013) Chromatin states at ribosomal DNA loci. BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 1829 (3-4). pp. 405-417. ISSN 1874-9399, 0006-3002
Full text not available from this repository. (Request a copy)Abstract
Eukaryotic transcription of ribosomal RNAs (rRNAs) by RNA polymerase I can account for more than half of the total cellular transcripts depending on organism and growth condition. To support this level of expression, eukaryotic rRNA genes are present in multiple copies. Interestingly, these genes co-exist in different chromatin states that may differ significantly in their nucleosome content and generally correlate well with transcriptional activity. Here we review how these chromatin states have been discovered and characterized focusing particularly on their structural protein components. The establishment and maintenance of rRNA gene chromatin states and their impact on rRNA synthesis are discussed. This article is part of a Special Issue entitled: Transcription by Odd Pols. (C) 2012 Elsevier B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | RNA-POLYMERASE-I; UPSTREAM BINDING-FACTOR; TRANSCRIPTIONALLY ACTIVE CHROMATIN; NON-TRANSCRIBED REGIONS; XENOPUS-LAEVIS OOCYTES; GENE CHROMATIN; SACCHAROMYCES-CEREVISIAE; PHYSARUM-POLYCEPHALUM; NUCLEOLAR CHROMATIN; FACTOR UBF; Chromatin; Transcription; Ribosomal RNA genes; Ribosomal DNA;HMG-box protein; RNA polymerase I; Nucleosome |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Herbert Tschochner Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Dr. Joachim Griesenbeck |
| Depositing User: | Petra Gürster |
| Date Deposited: | 27 May 2020 10:50 |
| Last Modified: | 27 May 2020 10:50 |
| URI: | https://pred.uni-regensburg.de/id/eprint/17048 |
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