Niemeyer, P. and Andereya, S. and Angele, P. and Ateschrang, A. and Aurich, M. and Baumann, M. and Behrens, P. and Bosch, U. and Erggelet, C. and Fickert, S. and Fritz, J. and Gebhard, H. and Gelse, K. and Guenther, D. and Hoburg, A. and Kasten, P. and Kolombe, T. and Madry, H. and Marlovits, S. and Meenen, N. M. and Mueller, P. E. and Noeth, U. and Petersen, J. P. and Pietschmann, M. and Richter, W. and Rolauffs, B. and Rhunau, K. and Schewe, B. and Steinert, A. and Steinwachs, M. R. and Welsch, G. H. and Zinser, W. and Albrecht, D. (2013) Autologous Chondrocyte Implantation (ACI) for Cartilage Defects of the Knee: A Guideline by the Working Group "Tissue Regeneration" of the German Society of Orthopaedic Surgery and Traumatology (DGOU). ZEITSCHRIFT FUR ORTHOPADIE UND UNFALLCHIRURGIE, 151 (1). pp. 38-47. ISSN 1864-6697, 1864-6743
Full text not available from this repository. (Request a copy)Abstract
Autologous chondrocyte transplantation/implantation (ACT/ACI) is an established and recognised procedure for the treatment of localised fullthickness cartilage defects of the knee. The present review of review of group "Clinical Tissue Regeneration" of the German Society of Orthopaedics and Traumatology (DGOU) describes the biology and function of healthy articular cartilage, the present state of knowledge concerning potential consequences of primary cartilage lesions and the suitable indication for ACI. Based on current evidence, an indication for ACI is given for symptomatic cartilage defects starting from defect sizes of more than 3-4 cm(2); in the case of young and active sports patients at 2.5 cm(2). Advanced degenerative joint disease is the single most important contraindication. The review gives a concise overview on important scientific background, the results of clinical studies and discusses advantages and disadvantages of ACI.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | THICKNESS CHONDRAL DEFECTS; BILAYER COLLAGEN MEMBRANE; BONE-MARROW STIMULATION; TERM-FOLLOW-UP; ARTICULAR-CARTILAGE; OSTEOCHONDRAL DEFECTS; SUBCHONDRAL BONE; RANDOMIZED-TRIAL; MICROFRACTURE TECHNIQUE; SURGICAL-MANAGEMENT; knee joint; cartilage defect; cartilage repair; recommendations; osteoarthritis |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Unfallchirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 24 Apr 2020 11:59 |
| Last Modified: | 24 Apr 2020 11:59 |
| URI: | https://pred.uni-regensburg.de/id/eprint/17187 |
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