Anwander, Melissa and Rosentritt, Martin and Schneider-Feyrer, Sibylle and Hahnel, Sebastian (2017) Biofilm formation on denture base resin including ZnO, CaO, and TiO2 nanoparticles. JOURNAL OF ADVANCED PROSTHODONTICS, 9 (6). pp. 482-485. ISSN 2005-7806, 2005-7814
Full text not available from this repository. (Request a copy)Abstract
PURPOSE. This laboratory study aimed to investigate the effect of doping an acrylic denture base resin material with nanoparticles of ZnO, CaO, and TiO2 on biofilm formation. MATERIALS AND METHODS. Standardized specimens of a commercially available cold-curing acrylic denture base resin material were doped with 0.1, 0.2, 0.4, or 0.8 wt% commercially available ZnO, CaO, and TiO2 nanopowder. Energy dispersive X-ray spectroscopy (EDX) was used to identify the availability of the nanoparticles on the surface of the modified specimens. Surface roughness was determined by employing a profilometric approach; biofilm formation was simulated using a monospecies Candida albicans biofilm model and a multispecies biofilm model including C. albicans, Actinomyces naeslundii, and Streptococcus gordonii. Relative viable biomass was determined after 20 hours and 44 hours using a MTT-based approach. RESULTS. No statistically significant disparities were identified among the various materials regarding surface roughness and relative viable biomass. CONCLUSION. The results indicate that doping denture base resin materials with commercially available ZnO, CaO, or TiO2 nanopowders do not inhibit biofilm formation on their surface. Further studies might address the impact of varying particle sizes as well as increasing the fraction of nanoparticles mixed into the acrylic resin matrix.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ZINC-OXIDE NANOPARTICLES; STOMATITIS; ETIOLOGY; Biofilm; Denture; Nanoparticles; PMMA; Candida albicans |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Zahnärztliche Prothetik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:18 |
| Last Modified: | 01 Mar 2019 07:14 |
| URI: | https://pred.uni-regensburg.de/id/eprint/1720 |
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