Wirz, S. and Wiese, C. H. R. and Zimmermann, M. and Junker, U. and Heuser-Grannemann, E. and Schenk, M. (2013) Rapid release fentanyl administration forms. Comments of the Working Group on Tumor Pain of the German Pain Society. SCHMERZ, 27 (1). 76-+. ISSN 0932-433X, 1432-2129
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The spectrum of indications for rapid release fentanyl preparations is controversial. For this reason the Working Group on Tumor Pain will formulate comments on how to deal with these substances. Breakthrough pain should receive individualized therapy; therefore, the use of opioids of various galenic formulations seems to be advisable. New rapid release fentanyl preparations are suitable for alleviating spontaneous breakthrough pain in tumor patients due to a rapid but short-acting effect. However, a prior optimization of the analgesic basis medication is absolutely necessary. Uncontrolled prescription for non-cancer pain must be criticized due to the problem of addiction. The medical profession should be informed about the benefits of rapid release fentanyl preparations but must also be made aware of the risk of a rapid development of addiction and tolerance. A self-commitment of the pharmaceutical industry to waive advertising for the dangerous off-label use would be desirable. In the opinion of the Working Group on Tumor Pain the use of fentanyl should be openly discussed and further scientific investigations are imperative with the aim of formulating clear recommendations.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BREAKTHROUGH CANCER PAIN; DOUBLE-BLIND; OPEN-LABEL; MU-G; PREVALENCE; SPRAY; CROSSOVER; CITRATE; DEFINITION; MANAGEMENT; Breakthrough pain; Pain management; Opioid dependence; Fentanyl; Analgesics, short-acting |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 27 Apr 2020 05:24 |
| Last Modified: | 27 Apr 2020 05:24 |
| URI: | https://pred.uni-regensburg.de/id/eprint/17212 |
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