Preoperative diagnosis of thyroid adenomas using high resolution contrast-enhanced ultrasound (CEUS)

Agha, A. and Jung, E. M. and Janke, M. and Hornung, M. and Georgieva, M. and Schlitt, H. J. and Schreyer, A. G. and Strosczcynski, C. and Schleder, S. (2013) Preoperative diagnosis of thyroid adenomas using high resolution contrast-enhanced ultrasound (CEUS). CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 55 (4). pp. 403-409. ISSN 1386-0291, 1875-8622

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Abstract

To evaluate the impact of high-resolution contrast-enhanced ultrasound (CEUS), Color Coded and Power Doppler Sonography (CCDS/PD), in the preoperative recognition of thyroid adenomas. A total of 64 patients (36 female, median age 54 years) underwent surgery for thyroid adenoma. CEUS with linear multifrequency probes (6-9 or 6-15 MHz) and CCDS/PD was performed in all patients preoperatively by an experienced examiner and images were stored in PACS. Reading of the ultrasound images was performed in consensus by two experienced radiologists. Histopathology was achieved as standard of reference in all patients. Median diameter of the tumor lesions was 27 mm. 31 nodules were found on the left side. In B-Scan mode 13 (20%) adenomas showed complex cystic echo pattern and 44 (69%) had a complete and sharp hypoechoic edge. 43 (67%) thyroid adenomas had strong hypervascularization in CCDS/PD. In 61 (95%) adenomas early contrast enhancement was present in CEUS and 50 (78%) adenomas proved no wash-out or central wash-out with persisting edge enhancement. In 47 (73%) cases early contrast enhancement was combined with no washout or with central wash-out with persisting edge enhancement. 45 (70%) thyroid lesions had preoperatively been classified as benign lesions correctly. Dynamic evaluation of microcirculation by CEUS and CCDS/PD enables a more reliable preoperative characterization of thyroid adenomas.

Item Type: Article
Uncontrolled Keywords: DEGUM MULTICENTER TRIAL; FOCAL LIVER-LESIONS; NODULES; ACCURACY; MALIGNANCY; CEUS; power doppler; ultrasound; thyroid adenoma
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 28 Apr 2020 08:21
Last Modified: 28 Apr 2020 08:21
URI: https://pred.uni-regensburg.de/id/eprint/17318

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