Heibl, M. and Jung, E. M. and Beyer, L. and Wohlgemuth, W. A. and Stroszczynski, C. and Wiggermann, P. (2013) Aggregated time intensity curves after transarterial chemoembolization with degradable starch microspheres: A feasibility study. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 55 (4). pp. 417-421. ISSN 1386-0291, 1875-8622
Full text not available from this repository. (Request a copy)Abstract
PURPOSE: To evaluate tumor perfusion by means of dynamic contrast-enhanced ultrasonography (DCEUS) and aggregated time intensity curves (TICs) after transarterial chemoembolization with degradable starch microspheres (DSM-TACE). MATERIAL AND METHODS: 18 patients underwent 36 DCEUS examinations conducted via contrast agent application before and after DSM-TACE. Based on time intensity curves (TICs), we analyzed the microcirculation of the embolized HCC lesions with a dedicated perfusion software. RESULTS: Signal intensity was significantly reduced (p <= 0.001) after DSM-TACE at all time points measured. The mean signal intensity after 5, 10, 15, 20 and 25 s was 375.18 +/- 16.41, 455.66 +/- 17.92, 294.47 +/- 19.91, 246.51 +/- 20.99 and 173.45 +/- 25.80 before TACE and 49.47 +/- 2.43, 49.51 +/- 2.40, 37.40 +/- 2.45, 27.48 +/- 2.65 and 27.96 +/- 3.01 after TACE. CONCLUSION: In this study, tumor perfusion could be accurately evaluated by means of DCEUS and aggregated TICs after DSM-TACE.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CONTRAST-ENHANCED ULTRASOUND; HEPATOCELLULAR-CARCINOMA; ARTERIAL CHEMOEMBOLIZATION; HEPATIC-ARTERY; LIVER; CEUS; COMPLICATIONS; CANCER; HCC; DSM; HCC; DSM-TACE; DCE-US; TIC |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 28 Apr 2020 08:23 |
| Last Modified: | 28 Apr 2020 08:23 |
| URI: | https://pred.uni-regensburg.de/id/eprint/17319 |
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