Matterne, Uwe and Apfelbacher, Christian J. and Vogelgsang, Lena and Loerbroks, Adrian and Weisshaar, Elke (2013) Incidence and Determinants of Chronic Pruritus: A Population-based Cohort Study. ACTA DERMATO-VENEREOLOGICA, 93 (5). pp. 532-537. ISSN 0001-5555, 1651-2057
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Epidemiological data on chronic pruritus (>6 weeks) in the general population are sparse. We aimed to provide data on the incidence and prevalence of chronic pruritus, and identify its determinants based on cross-sectional and longitudinal analyses. A cohort of 1,190 participants from a cross-sectional baseline-study (response rate: 57.8%) was followed up after one year. The questionnaire assessed occurrence of chronic pruritus, medical, lifestyle and psychosocial variables. Incident chronic pruritus was defined as reported chronic pruritus at follow-up in those subjects free-of-the-symptom at baseline. Cross-sectional analyses of data from the follow-up assessments addressed potential associations of medical, lifestyle and psychosocial factors with prevalent chronic pruritus. Longitudinal analyses examined sociodemographic factors as potential predictors of incident chronic pruritus. The follow-up response rate was 83.1%. The mean age of subjects was 56 years, and 58% were female. The 12-month cumulative-incidence equalled 7.0% (95% confidence interval (95% CI) 5.2-9.2%. Lifetime prevalence was 25.5% (95% CI 21.8-27.8%). Incidence was significantly associated with age. Determinants of prevalent chronic pruritus in multivariable analyses were: liver disease, asthma, eczema and dry skin within the medical domain, an elevated body mass index within the lifestyle domain and higher anxiety scores within the psychosocial domain. Findings suggest a considerable 12-month incidence and lifetime prevalence and provide important directions for future research.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CHRONIC IDIOPATHIC URTICARIA; GENERAL-POPULATION; SKIN MORBIDITY; LIFE EVENTS; PSORIASIS; ITCH; PREVALENCE; RISK; CARE; HYPOCHONDRIASIS; chronic pruritus; incidence; prevalence; longitudinal; predictors; determinants |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Institut für Epidemiologie und Präventivmedizin Medicine > Institut für Epidemiologie und Präventivmedizin > Medical Sociology |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 28 Apr 2020 08:40 |
| Last Modified: | 28 Apr 2020 08:40 |
| URI: | https://pred.uni-regensburg.de/id/eprint/17324 |
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