Depressive disorders in internal and neurological diseases

Juckel, G. and Norra, C. and Herpertz, S. and Baghai, T. C. and Lieb, M. and Schaefer, M. (2013) Depressive disorders in internal and neurological diseases. NERVENHEILKUNDE, 32 (6). pp. 381-387. ISSN 0722-1541

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Abstract

The high coincidence of somatic disorders and depression demonstrates the importance of a general screening for depressive disorders also in somatic disciplines. With respect to prevalence, pathophysiology, prognostic significance, and treatment of depressive syndromes current knowledge on depression in selected somatic diseases are presented: diabetes mellitus, cardiovascular diseases, liver and bowel disease, Parkinson's disease as well as multiple sclerosis. Overall an unfavorable lifestyle (e.g lack of exercise, obesity, smoking, high alcohol consumption) appears to play a crucial role for the increase in incidence of somatic diseases in patients with depressive disorders. This applies to the implementation of therapeutic strategies, too. Likewise, biological changes (stress hormone and immune activation) are discussed as possible causes of increased morbidity and mortality. In general, substantial epidemiological data, interdisciplinary clinical and therapeutic studies and basic scientific. research on the pathophysiology of comorbid depression in physical illness are needed.

Item Type: Article
Uncontrolled Keywords: CHRONIC HEPATITIS-C; IRRITABLE-BOWEL-SYNDROME; CORONARY-ARTERY-DISEASE; MULTIPLE-SCLEROSIS PATIENTS; CONVERTING-ENZYME GENE; MAJOR DEPRESSION; MYOCARDIAL-INFARCTION; INTERFERON-ALPHA; DOUBLE-BLIND; CARDIOVASCULAR-DISEASE; Depression; somatic disease; antidepressants
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Depositing User: Petra Gürster
Date Deposited: 27 May 2020 07:42
Last Modified: 27 May 2020 07:42
URI: https://pred.uni-regensburg.de/id/eprint/17399

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