Is There a Negative Interpretation Bias in Depressed Patients? An Affective Startle Modulation Study

Kaese, Mirjam and Dresler, Thomas and Andreatta, Marta and Ehlis, Ann-Christine and Wolff, Babette and Kittel-Schneidera, Sarah and Polak, Thomas and Fallgatter, Andreas J. and Muehlberger, Andreas (2013) Is There a Negative Interpretation Bias in Depressed Patients? An Affective Startle Modulation Study. NEUROPSYCHOBIOLOGY, 67 (4). pp. 201-209. ISSN 0302-282X, 1423-0224

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Abstract

Background/Aims: Scientists proposed that patients with depression favour negative interpretations when appraising ambiguity. As self-report measures seem prone to response bias, implicit measures of emotional valence should be additionally used. Methods: A total of 16 patients with depression and 19 controls underwent an acoustic imagery task comprising neutral and negative words, as well as ambiguous words that could be understood either way. Affective startle modulation and direct interrogation were used to assess implicit and explicit emotional valence, respectively. We expected a negative bias for ambiguous words in the patient group, resulting in augmented startle magnitudes and preference for negative interpretations of the ambiguous words in the interrogation. Results: Surprisingly, both groups preferred neutral interpretations and showed augmented startle magnitudes to ambiguous words. Furthermore, both groups displayed an emotional startle potentiation for negative words. Conclusion: In summary, our results do not confirm a negative interpretation bias or a blunted emotional response in patients with major depression. The mismatch between self-report and affective startle reaction to ambiguous targets might reflect defensive mobilization or attention effects. Copyright (c) 2013 S. Karger AG, Basel

Item Type: Article
Uncontrolled Keywords: AUDITORY-EVOKED RESPONSE; PREPULSE INHIBITION; INDIVIDUAL-DIFFERENCES; EYEBLINK RESPONSE; EMOTION; ANXIETY; REFLEX; BLINK; MOOD; ATTENTION; Depression; Affective startle modulation; Ambiguity; Interpretation bias; Cognitive theory
Subjects: 100 Philosophy & psychology > 150 Psychology
Divisions: Human Sciences > Institut für Psychologie > Lehrstuhl für Klinische Psychologie und Psychotherapie - Lehrstuhl für Psychologie VIII - Prof. Dr. Andreas Mühlberger
Depositing User: Dr. Gernot Deinzer
Date Deposited: 29 Apr 2020 05:26
Last Modified: 29 Apr 2020 05:26
URI: https://pred.uni-regensburg.de/id/eprint/17412

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