Guelak, Samet and Stepanek, Ondrej and Malberg, Jennifer and Rad, Babak Rezaei and Kotora, Martin and Wolf, Robert and Jacobi von Wangelin, Axel (2013) Highly chemoselective cobalt-catalyzed biaryl coupling reactions. CHEMICAL SCIENCE, 4 (2). pp. 776-784. ISSN 2041-6520,
Full text not available from this repository. (Request a copy)Abstract
A practical cobalt-catalyzed hetero-biaryl coupling reaction between aryl chlorides and arylmagnesium halides with unprecedented selectivity has been developed. The protocol utilizes 1 mol% of cheap Co(acac)(3) as pre-catalyst and effects clean reactions of deactivated chlorostyrenes with only 1.1 equiv. of the Grignard reagent under mild conditions (30 degrees C, 5-30 min). Highly chemoselective reactions were realized even in the presence of activated bromoarenes. The olefin substituent facilitates the activation of the C-Cl bond by coordination to the catalyst. Kinetic studies indicate the operation of an arylcobaltate(I) catalyst species. Catalyst formation during the induction period was studied in the presence of cobalt(III), (I), and (-I) pre-catalysts.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ARYL GRIGNARD-REAGENTS; ALKYL-HALIDES; STYRENE DERIVATIVES; P-CHLOROSTYRENE; COMPLEXES; IRON; CHLORIDES; POLYMERIZATION; ELECTROPHILES; DIMERIZATION; |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Anorganische Chemie > Arbeitskreis Prof. Dr. Robert Wolf Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Prof. Dr. Axel Jacobi von Wangelin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 29 Apr 2020 10:11 |
| Last Modified: | 29 Apr 2020 10:11 |
| URI: | https://pred.uni-regensburg.de/id/eprint/17518 |
Actions (login required)
 |
View Item |
