Bowen, Michael T. and Neumann, Inga D. (2017) Rebalancing the Addicted Brain: Oxytocin Interference with the Neural Substrates of Addiction. TRENDS IN NEUROSCIENCES, 40 (12). pp. 691-708. ISSN 0166-2236, 1878-108X
Full text not available from this repository. (Request a copy)Abstract
Drugs that act on the brain oxytocin (OXT) system may provide a much-needed treatment breakthrough for substance-use disorders. Targeting the brain OXT system has the potential to treat addiction to all major classes of addictive substance and to intervene across all stages of the addiction cycle. Emerging evidence suggests that OXT is able to interfere with such a wide range of addictive behaviours for such a wide range of addictive substances by rebalancing core neural systems that become dysregulated over the course of addiction. By improving our understanding of these interactions between OXT and the neural substrates of addiction, we will not only improve our understanding of addiction, but also our ability to effectively treat these devastating disorders.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CONDITIONED PLACE PREFERENCE; MEDIAL PREFRONTAL CORTEX; ALCOHOL-USE DISORDER; METHAMPHETAMINE-SEEKING BEHAVIOR; RECEPTOR-RECEPTOR INTERACTIONS; NUCLEUS-ACCUMBENS DOPAMINE; SOCIAL ANXIETY DISORDER; VENTRAL TEGMENTAL AREA; INTRANASAL OXYTOCIN; PARAVENTRICULAR NUCLEUS; |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Zoologie > Tierphysiologie/Neurobiologie (Prof. Dr. Inga Neumann) |
| Depositing User: | Petra Gürster |
| Date Deposited: | 14 Dec 2018 13:19 |
| Last Modified: | 10 Sep 2020 06:18 |
| URI: | https://pred.uni-regensburg.de/id/eprint/1787 |
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