Teusch, Veronika I. and Wohlgemuth, Walter A. and Hammer, Simone and Piehler, Armin P. and Mueller-Wille, Rene and Goessmann, Holger and Uller, Wibke (2017) Ethanol-Gel Sclerotherapy of Venous Malformations: Effectiveness and Safety. AMERICAN JOURNAL OF ROENTGENOLOGY, 209 (6). pp. 1390-1395. ISSN 0361-803X, 1546-3141
Full text not available from this repository. (Request a copy)Abstract
OBJECTIVE. In the treatment of venous malformations, ethanol may be administered in a gelified form to increase local effects and reduce systemic ones. The purpose of this prospective study was to evaluate the efficacy and safety of a commercially available viscous ethanol gel in the treatment of venous malformations. SUBJECTS AND METHODS. Thirty-one patients (mean age, 23.4 years; age range, 6.6-46.5 years) with venous malformations were prospectively scheduled for two ethanol-gel sclerotherapy sessions. Venous malformations were located at the lower extremity (n = 18), the upper extremity (n = 9), and the face (n = 4). Questionnaires to assess pain, clinical examinations, professional photographs, and contrast-enhanced MRI of the venous malformations were performed before and after therapy to measure therapy-induced changes. Two experienced radiologists blinded to the examination date and clinical status compared photographs and MR images before and after treatment. RESULTS. A mean of 4.2 mL of ethanol gel were administered per session. The technical success rate was 100%. Clinical success, defined as improvement or resolution of symptoms, was noted in 81% of patients. Mean pain score decreased, and the difference was statistically significant (3.9 vs 3.1, p = 0.005). In 54 treatment sessions where follow-up was available, four minor complications occurred. Comparison of photographs and MR images before and after treatment showed improvement in 35% and 93% of patients, respectively. CONCLUSION. Ethanol gel is an effective and safe sclerosing agent in the treatment of venous malformations.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | FLOW VASCULAR MALFORMATIONS; CARDIOVASCULAR COLLAPSE; SCLEROSING AGENT; COMPLICATIONS; PARAMETERS; NECK; HEAD; ethanol gel; sclerotherapy; venous malformation |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:19 |
| Last Modified: | 28 Feb 2019 10:48 |
| URI: | https://pred.uni-regensburg.de/id/eprint/1788 |
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