Impact of multidetector computed tomography on the diagnosis and treatment of patients with systemic inflammatory response syndrome or sepsis

Schleder, S. and Luerken, L. and Dendl, L. M. and Redel, A. and Selgrad, M. and Renner, P. and Stroszczynski, C. and Schreyer, A. G. (2017) Impact of multidetector computed tomography on the diagnosis and treatment of patients with systemic inflammatory response syndrome or sepsis. EUROPEAN RADIOLOGY, 27 (11). pp. 4544-4551. ISSN 0938-7994, 1432-1084

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Abstract

Objectives To evaluate the impact of CT scans on diagnosis or change of therapy in patients with systemic inflammatory response syndrome (SIRS) or sepsis and obscure clinical infection. Methods CT records of patients with obscure clinical infection and SIRS or sepsis were retrospectively evaluated. Both confirmation of and changes in the diagnosis or therapy based on CT findings were analysed by means of the hospital information system and radiological information system. A subgroup analysis included differences with regard to anatomical region, medical history and referring department. Results Of 525 consecutive patients evaluated, 59% had been referred from internal medicine and 41% from surgery. CT examination had confirmed the suspected diagnosis in 26% and had resulted in a different diagnosis in 33% and a change of therapy in 32%. Abdominal scans yielded a significantly higher (p=0.013) change of therapy rate (42%) than thoracic scans (22%). Therapy was changed significantly more often (p=0.016) in surgical patients (38%) than in patients referred from internal medicine (28%). Conclusions CT examination for detecting an unknown infection focus in patients with SIRS or sepsis is highly beneficial and should be conducted in patients with obscure clinical infection.

Item Type: Article
Uncontrolled Keywords: SEPTIC SHOCK; CT; DEFINITIONS; Computed tomography; Sepsis; Infection; Systemic inflammatory response syndrome; Infection control
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Anästhesiologie
Medicine > Lehrstuhl für Innere Medizin I
Depositing User: Dr. Gernot Deinzer
Date Deposited: 14 Dec 2018 13:19
Last Modified: 19 Feb 2019 07:59
URI: https://pred.uni-regensburg.de/id/eprint/1951

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