On the use of multi-dimensional scaling and electromagnetic tracking in high dose rate brachytherapy

Goetz, Th I. and Ermer, M. and Salas-Gonzalez, D. and Kellermeier, M. and Strnad, V. and Bert, Ch and Hensel, B. and Tome, A. M. and Lang, E. W. (2017) On the use of multi-dimensional scaling and electromagnetic tracking in high dose rate brachytherapy. PHYSICS IN MEDICINE AND BIOLOGY, 62 (20). pp. 7959-7980. ISSN 0031-9155, 1361-6560

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Abstract

High dose rate brachytherapy affords a frequent reassurance of the precise dwell positions of the radiation source. The current investigation proposes a multi-dimensional scaling transformation of both data sets to estimate dwell positions without any external reference. Furthermore, the related distributions of dwell positions are characterized by uni-or bi-modal heavy-tailed distributions. The latter are well represented by alpha-stable distributions. The newly proposed data analysis provides dwell position deviations with high accuracy, and, furthermore, offers a convenient visualization of the actual shapes of the catheters which guide the radiation source during the treatment.

Item Type: Article
Uncontrolled Keywords: ALPHA-STABLE DISTRIBUTIONS; INTERSTITIAL BRACHYTHERAPY; BREAST IRRADIATION; BAYESIAN-INFERENCE; QUALITY-ASSURANCE; UNIMODALITY; PROSTATE; SURGERY; multi-dimensional scaling; electromagnetic tracking; brachytherapy; Levy distributions; hartigan-dip-test
Subjects: 500 Science > 570 Life sciences
Divisions: Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie
Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Elmar Lang
Depositing User: Dr. Gernot Deinzer
Date Deposited: 14 Dec 2018 13:19
Last Modified: 01 Mar 2019 08:17
URI: https://pred.uni-regensburg.de/id/eprint/1989

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