Buchner, Markus and Ngoensawat, Umphan and Schenck, Milena and Fenzl, Christoph and Wongkaew, Nongnoot and Matlock-Colangelo, Lauren and Hirsch, Thomas and Duerkop, Axel and Baeumner, Antje J. (2017) Embedded nanolamps in electrospun nanofibers enabling online monitoring and ratiometric measurements. JOURNAL OF MATERIALS CHEMISTRY C, 5 (37). pp. 9712-9720. ISSN 2050-7526, 2050-7534
Full text not available from this repository. (Request a copy)Abstract
A multifunctional composite nanomaterial based on nanofiber embedding upconversion nanoparticles (UCNPs) is designed to address the common limitations of bioanalysis including the colloidal stability of nanoparticles, high background signals and small sample volumes. We fabricate thin and uniform electrospun polyvinylpyrrolidone (PVP) nanofibers with a diameter of 170 +/- 80 nm, containing up to 254 +/- 9 mg mL(-1) of non-agglomerated UCNPs. On distributing these nanofibers in a microfluidic channel a 50-fold increase in luminescence over dispersed particles can be obtained. A versatile miniaturized platform is created to work with small sample volumes by transferring the upconversion nanofibers into microfluidic channels. Fast and reproducible analytical signal response to their environment is demonstrated by taking advantage of the isotope effect between H2O and D2O upon 980 nm excitation. Furthermore, relevance to analytical applications employing energy transfer was confirmed using the spectral overlap of the green UCNP emission with the absorption spectra of a dye. At minute optical path lengths (e.g. 50 mu m) the luminescence properties of the UCNPs help in avoiding the most disturbing light scattering effects of the excitation source and channel geometries. This new nanomaterial platform enables rapid, simple and reliable online monitoring in microfluidic systems, medical applications (e.g. in-tissue, in vivo) and anti-counterfeiting in contrast to solution-based UCNP applications.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | UP-CONVERSION NANOPARTICLES; SURFACE MODIFICATION; COMPOSITE FIBERS; POLYMER; LUMINESCENCE; PARAMETERS; MORPHOLOGY; NANOTUBES; SYSTEMS; DESIGN; |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Antje J. Bäumner, formerly Prof. Wolfbeis) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:19 |
| Last Modified: | 27 Feb 2019 07:32 |
| URI: | https://pred.uni-regensburg.de/id/eprint/2018 |
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