Boronic acid-modified alginate enables direct formation of injectable, self-healing and multistimuli-responsive hydrogels

Pettignano, Asja and Grijalvo, Santiago and Haering, Marleen and Eritja, Ramon and Tanchoux, Nathalie and Quignard, Francoise and Diaz Diaz, David (2017) Boronic acid-modified alginate enables direct formation of injectable, self-healing and multistimuli-responsive hydrogels. CHEMICAL COMMUNICATIONS, 53 (23). pp. 3350-3353. ISSN 1359-7345, 1364-548X

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Abstract

One-step functionalization of alginate with boronic acid groups allowed spontaneous formation of biocompatible hydrogels under basic conditions without additional complementary molecules or crosslinking agents. The dynamic nature of boronate ester bonds formed with vicinal diols present on alginate pyranose rings provided remarkable self-healing, injectable and multi-stimuli responsive properties to the material.

Item Type: Article
Uncontrolled Keywords: BIOMEDICAL APPLICATIONS; CHEMISTRY; DELIVERY; GELS; PH;
Subjects: 600 Technology > 660 Chemical engineering
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Prof. Dr. David Díaz Díaz
Depositing User: Dr. Gernot Deinzer
Date Deposited: 14 Dec 2018 13:00
Last Modified: 26 Feb 2019 07:22
URI: https://pred.uni-regensburg.de/id/eprint/207

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