Gorris, Hans H. and Resch-Genger, Ute (2017) Perspectives and challenges of photon-upconversion nanoparticles - Part II: bioanalytical applications. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409 (25). pp. 5875-5890. ISSN 1618-2642, 1618-2650
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In Part II of this review series on lanthanide-doped photon-upconversion nanoparticles (UCNPs), we present and critically discuss the performance and suitability of UCNPs as background-free luminescent reporters in bioimaging and bioanalytical applications. The preparation of a biocompatible nanoparticle surface is an integral step for all life - science-related applications. UCNPs have found their way into a large number of diagnostic platforms, homogeneous and heterogeneous assay formats, and sensor applications. Many bioanalytical detection schemes involve Forster resonance energy transfer (FRET), which is still debated for UCNPs and needs to be much improved. The need for dedicated and standardized instruments as well as recent studies on the dissolution and potential toxicity of UCNPs are addressed. Finally we outline future trends and challenges in the field of upconversion.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | UPCONVERTING LUMINESCENT NANOPARTICLES; RESONANCE ENERGY-TRANSFER; LANTHANIDE-DOPED NANOCRYSTALS; CONVERTING PHOSPHOR REPORTERS; CORE-SHELL NANOSTRUCTURES; LATERAL FLOW ASSAY; IN-VIVO DETECTION; QUANTUM-DOT FRET; RATIOMETRIC DETECTION; AQUEOUS SUSPENSIONS; Lanthanides; Nanomaterials; Fluorescence; Assay; Background-free imaging; FRET; Sensor |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik |
| Depositing User: | Petra Gürster |
| Date Deposited: | 14 Dec 2018 13:19 |
| Last Modified: | 04 Sep 2020 06:35 |
| URI: | https://pred.uni-regensburg.de/id/eprint/2137 |
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