Pregler, B. and Beyer, L. P. and Wiesinger, I. and Niessen, C. and Jung, E. M. and Stroszczynski, C. and Wiggermann, P. (2016) Microwave ablation of large HCC lesions: Added value of CEUS examinations for ablation success control. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 64 (3). pp. 483-489. ISSN 1386-0291, 1875-8622
Full text not available from this repository. (Request a copy)Abstract
PURPOSE: To assess the value of dynamic contrast enhanced ultrasound (CEUS) for the detection of residual tumor tissue day 1 after microwave ablation (MWA) of large hepatocellular carcinoma (HCC) compared to MRI. MATERIAL AND METHODS: 30 consecutive patients (5 females, 25 males, mean age 64 years, age range 54-73 years) with an untreated HCC lesion larger than or equal to 3 cm underwent percutaneous MWA between 03/2014 and 04/2016. 1 patient was excluded because of an artificial pacemaker. All remaining 29 patients underwent 3-T MRI with liver-specific contrast agent and CEUS 1 day after ablation to detect residual tumor tissue. The 6-week follow-up including CEUS and MRI was defined as the reference standard. RESULTS: Complete ablation was achieved in 23 of 29 treated lesions (79%). The sensitivities and specificities for the detection of residual tumor tissue on day 1 were 100% and 83% for CEUS and 87% and 67% for MRI resp. without the differences being statistically significant. CONCLUSION: CEUS allows a reliable assessment of therapeutic success of percutaneous ablation of large HCC lesions one day after the ablation. Its ability to visualize reactive periablation perfusion changes in real-time might be of advantage in the depiction of residual tumor tissue when compared to MRI imaging alone.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HEPATOCELLULAR-CARCINOMA; RADIOFREQUENCY ABLATION; CIRRHOSIS; SPECTRUM; LIVER; Contrast-enhanced ultrasound (CEUS); microwave ablation (MWA); hepatocellular carcinoma (HCC); imaging findings |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 01 Mar 2019 12:36 |
| Last Modified: | 11 Mar 2019 09:40 |
| URI: | https://pred.uni-regensburg.de/id/eprint/2252 |
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