Vitamin D and depression

Lange, Katharina M. and Hauser, Joachim and Kaunzinger, Ivo and Makulska-Gertruda, Ewelina and Nakamura, Yukiko and Reissmann, Andreas and Lange, Klaus W. (2016) Vitamin D and depression. AGRO FOOD INDUSTRY HI-TECH, 27 (2). XXIX-XXXII. ISSN 1722-6996, 2035-4606

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Abstract

Vitamin D has been proposed to be involved in various functions of the central nervous system and vitamin D deficiency has been associated with a number of psychiatric conditions. The present short review provides an overview of the potential role of vitamin D in the etiology and therapy of depression. Recent meta-analyses have indicated an inverse association between 25-hydroxyvitamin D (25(OH)D) levels and the risk of depression, i.e. low vitamin D concentrations are associated with depression while higher serum 25(OH)D levels appear to protect against depression. Randomized controlled trials are needed in order to determine whether this association is causal and to assess the effects of vitamin D administration in the prevention and treatment of depression. Due to methodological problems of the available studies there is at present no clear evidence of an association between vitamin D status and depression.

Item Type: Article
Uncontrolled Keywords: RANDOMIZED CONTROLLED-TRIALS; 25-HYDROXYVITAMIN D LEVELS; POSTPARTUM DEPRESSION; BRAIN-DEVELOPMENT; D SUPPLEMENTATION; D DEFICIENCY; METAANALYSIS; ASSOCIATION; SYMPTOMS; RISK; Vitamin D; depression; mood; treatment
Subjects: 100 Philosophy & psychology > 150 Psychology
Divisions: Psychology and Pedagogy > Institut für Psychologie > Lehrstuhl für Psychologie III (Biologische, Klinische und Rehabilitationspsychologie) - Prof. Dr. Klaus W. Lange
Depositing User: Dr. Gernot Deinzer
Date Deposited: 12 Mar 2019 09:40
Last Modified: 12 Mar 2019 09:40
URI: https://pred.uni-regensburg.de/id/eprint/2273

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