Schmalz, G. and Widbiller, M. and Galler, K. M. (2016) Material Tissue Interaction-From Toxicity to Tissue Regeneration. OPERATIVE DENTISTRY, 41 (2). pp. 117-131. ISSN 0361-7734, 1559-2863
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The topic of material tissue interaction has gained increasing interest over recent decades from both the dental profession and the public. The primary goal initially was to avoid adverse reactions after the application of dental materials. New laboratory test methods have been developed, and currently premarket testing programs, which attempt to guarantee a basic level of patient safety, are legally required worldwide. The dentist is responsible for selecting the correct indication as well as the proper handling of any newly emerging risk. Apart from this phenomenon-oriented "inert materials concept," the "analytical concept" focuses primarily on analyzing the reasons for adverse reactions, and identifying their associated modifying factors, in order to prevent them or to develop new and more biocompatible materials. The "concept of bioactivity" involves addressing the possibility of positively influencing tissue by materials application, such as the generation of tertiary dentin or antibacterial effects. Finally, tissue regeneration may be supported and promoted by the use of various suitable materials (matrices/scaffolds) into which stem cells can migrate or be seeded, leading to cell differentiation and the generation of new tissue. These new dental materials must also fulfill additional requirements such as controlled degradability in order to be suitable for clinical use. Clearly, the field of material tissue interaction is complex and comprises a wide range of issues. To be successful as dentists in the future, practitioners should remain informed of these important new developments and have the argumentative competence to both properly advise and treat their patients.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MINERAL TRIOXIDE AGGREGATE; TRIETHYLENE-GLYCOL DIMETHACRYLATE; CALCIUM HYDROXIDE CEMENT; NECROTIC IMMATURE TEETH; ORAL LICHENOID LESIONS; DENTIN BONDING SYSTEM; PULP STEM-CELLS; BISPHENOL-A; COMPOSITE RESTORATIONS; PHOTODYNAMIC THERAPY; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Zahnerhaltung und Parodontologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 12 Mar 2019 09:43 |
| Last Modified: | 12 Mar 2019 09:43 |
| URI: | https://pred.uni-regensburg.de/id/eprint/2274 |
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