Breyer, Johannes and Denzinger, Stefan and Hartmann, Arndt and Otto, Wolfgang (2016) Downregulation of Checkpoint Protein Kinase 2 in the Urothelium of Healthy Male Tobacco Smokers. UROLOGIA INTERNATIONALIS, 97 (4). pp. 480-481. ISSN 0042-1138, 1423-0399
Full text not available from this repository. (Request a copy)Abstract
With this letter to the editor we present for the first time a study on CHEK2 expression in normal urothelium of healthy male smokers, former smokers and non-smokers. We could show a statistically significant downregulation of this DNA repair gene in current smokers compared to non-smokers, suggesting that smoking downregulates CHEK2 in normal urothelium, probably associated with an early step in carcinogenesis of urothelial bladder carcinoma. (C) 2016 S. Karger AG, Basel
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BLADDER-CANCER; RISK; Bladder; Bladder carcinoma; Immunohistochemistry; Transurethral resection; Etiology; Risk factor; CHEK2 |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Urologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 Mar 2019 08:55 |
| Last Modified: | 20 Mar 2019 08:55 |
| URI: | https://pred.uni-regensburg.de/id/eprint/2613 |
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