Foltan, Maik and Philipp, Alois and Gobolos, Laszlo and Holzamer, Andreas and Schneckenpointner, Roland and Lehle, Karla and Kornilov, Igor and Schmid, Christof and Lunz, Dirk (2019) Quantitative assessment of peripheral limb perfusion using a modified distal arterial cannula in venoarterial ECMO settings. PERFUSION-UK, 34 (6). pp. 503-507. ISSN 0267-6591, 1477-111X
Full text not available from this repository. (Request a copy)Abstract
In cases of severe cardiopulmonary deterioration, quick establishment of venoarterial extracorporeal membrane oxygenation (ECMO) represents a support modality. After successful arterial peripheral cannulation, a certain grade of peripheral limb malperfusion is a fairly common phenomenon. Detection of peripheral malperfusion is vital, since it can result in compartment syndrome or even loss of the affected limb. To prevent or resolve emerging lower limb ischaemia, a newly designed perfusion catheter is placed into the superficial femoral artery, distal to the arterial cannula via ECMO. The aim of our study was to evaluate flow and haemodynamic characteristics of this novel distal limb perfusion cannula for ECMO therapy and present these important findings for the first time. The distal perfusion cannula blood flow increases in linear correlation with ECMO blood flow The variability of distal perfusion cannula blood flow with a 15 Fr cannula ranges between 160 +/- 0.40 mL min(-1) at 1.5 L min(-1) ECMO flow rate and 480 +/- 80 mL min(-1) at 5.0 L min(-1) ECMO blood flow, respectively. Comparatively, the 17-Fr-sized cannula performs on a scale of 140 +/- 20 to 390 +/- 60 mL distal perfusion cannula blood flow at 1.5-5.0 L min(-1) ECMO blood flow, respectively. The quantitative assessment of the distal perfusion cannula blood flow has revealed that distal perfusion cannula blood flow can measure up to 10% of the ECMO blood flow. Furthermore, it has been also well demonstrated that the novel distal perfusion cannula is sufficient to compensate peripheral limb ischaemia.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | EXTRACORPOREAL MEMBRANE-OXYGENATION; COMPLICATIONS; ISCHEMIA; venoarterial extracorporeal membrane oxygenation; peripheral perfusion; limb perfusion; near infrared spectroscopy |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 31 Mar 2020 06:16 |
| Last Modified: | 31 Mar 2020 06:16 |
| URI: | https://pred.uni-regensburg.de/id/eprint/26343 |
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