Evert, K. and Stiegler, C. and Schaefer, C. and Palme, K. and Horndasch, E. and Reitinger, S. and Rau, B. M. and Dietmaier, W. and Evert, M. (2019) Successful pembrolizumab therapy in metastasized adenosquamous carcinoma of the colon. PATHOLOGE, 40 (5). pp. 540-545. ISSN 0172-8113, 1432-1963
Full text not available from this repository. (Request a copy)Abstract
Adenosquamous carcinoma (ASqC) is an exceedingly rare subtype of colorectal cancer without any known special guidelines for treatment. The biological behaviour and molecular background are widely unknown, although a few case studies report a worse prognosis compared to ordinary colorectal adenocarcinoma. We herein report for the first time the successful immune checkpoint inhibitor therapy in a 40-year-old patient suffering from metastasized right-sided colonic ASqC with unique molecular features, after having previously progressed under standard chemotherapy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MICROSATELLITE INSTABILITY; COLORECTAL-CANCER; PIK3CA MUTATION; PROGNOSTIC ROLE; Adenosquamous colorectal carcinoma; Immune checkpoint inhibition; FOLFOX4; Microsatellite instability |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Pathologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 31 Mar 2020 06:21 |
| Last Modified: | 31 Mar 2020 06:21 |
| URI: | https://pred.uni-regensburg.de/id/eprint/26353 |
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