Klingelhoeffer, Christoph and Obst, Annegret and Ettl, Tobias and Meier, Johannes and Mueller, Steffen and Reichert, Torsten and Spanier, Gerrit (2019) Severe postoperative dysphagia as an early predictor for decreased overall survival in patients with oral cancer. JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY, 47 (9). pp. 1363-1369. ISSN 1010-5182, 1878-4119
Full text not available from this repository. (Request a copy)Abstract
Objectives: The aim of this retrospective study was to analyze the early postoperative swallowing outcome in oral cancer patients considering risk factors and localization. Materials and methods: Four hundred patients with primary cases of oral cancer were included. Tumors' locations were categorized into four main groups (central, lateral, anterior and posterior). Swallowing function was evaluated at day 7 after surgery. Results: Ninety-eight percent (393/400) of the patients had a swallowing impairment including 41 (10.2%) patients who were unable to swallow. Strong risk factors with p values of 0.001 were tumor size, nodal stage, tracheotomy, insufficient dental status and reconstruction with a flap. The inability to swallow was increased at T1 und T2 patients, if they were reconstructed with a flap compared to patients who had a primary wound closure (p = 0.04). Decreased swallowing function was determined if the tumor was located central (OR = 1.8; p = 0.141) and additionally posterior (OR = 5.8; p = 0.110). Inability to swallow, even at that early point in time, (p = 0.001) was as significant as tumor size (p = 0.009) and nodal stage (p = 0.020), referring to overall survival. Conclusion: The impact of early dysphagia should not be underestimated. By considering swallowing impairment at the primary therapy patients can profit concerning survival and comorbidity. (C) 2019 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | FREE-FLAP RECONSTRUCTION; QUALITY-OF-LIFE; NECK-CANCER; FOREARM FLAP; SWALLOWING FUNCTION; PRIMARY CLOSURE; ADVANCED HEAD; OUTCOMES; RADIOTHERAPY; RESECTION; Dysphagia; Swallowing; Oral cancer; Flap reconstruction; Survival |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 31 Mar 2020 06:27 |
| Last Modified: | 31 Mar 2020 06:27 |
| URI: | https://pred.uni-regensburg.de/id/eprint/26356 |
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