Glutathione-Coated Magnetic Nanoparticles for One-Pot Synthesis of 1,4-Dihydropyridine Derivatives

Maleki, Behrooz and Atharifar, Hengameh and Reiser, Oliver and Sabbaghzadeh, Reihaneh (2019) Glutathione-Coated Magnetic Nanoparticles for One-Pot Synthesis of 1,4-Dihydropyridine Derivatives. POLYCYCLIC AROMATIC COMPOUNDS. ISSN 1040-6638, 1563-5333

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Abstract

A magnetic Fe3O4 supported glutathione catalyst was synthesized in a convenient and eco-friendly manner and characterized using FT-IR, XRD, TGA, TEM, VSM, EDX, and elemental analysis. This nano-organocatalyst exhibited excellent catalytic activity in the synthesis of a wide variety of 1,4-dihydropyridine derivatives. The catalyst was easily separated from the reaction mixture through using an external magnet and was reused in six consecutive runs with only a slight decrease in its catalytic activity. Other significant advantages of this method are shorter reaction time, excellent yield, simple work-up procedure, easy catalyst handling, and the high stability of the catalyst, which renders the protocol economic and sustainable.

Item Type: Article
Uncontrolled Keywords: POLYHYDROQUINOLINE DERIVATIVES; EFFICIENT CATALYST; 5-SUBSTITUTED 1H-TETRAZOLES; RECYCLABLE NANOCATALYST; HETEROGENEOUS CATALYST; HANTZSCH CONDENSATION; RECOVERABLE CATALYST; NANO-ORGANOCATALYST; FE3O4 NANOPARTICLES; REUSABLE CATALYST; 1; 4-Dihydropyridines; green chemistry; nanoferrite-anchored glutathione
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
Depositing User: Petra Gürster
Date Deposited: 31 Mar 2020 13:00
Last Modified: 31 Mar 2020 13:00
URI: https://pred.uni-regensburg.de/id/eprint/26607

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