Wildgruber, Moritz and Wrede, Christian E. and Zorger, Niels and Mueller-Wille, Rene and Hamer, Okka W. and Zeman, Florian and Stroszczynski, Christian and Heiss, Peter (2017) Computed tomography versus digital subtraction angiography for the diagnosis of obscure gastrointestinal bleeding. EUROPEAN JOURNAL OF RADIOLOGY, 88. pp. 8-14. ISSN 0720-048X, 1872-7727
Full text not available from this repository. (Request a copy)Abstract
Purpose: The diagnostic yield of computed tomography angiography (CTA) compared to digital subtraction angiography (DSA) for major obscure gastrointestinal bleeding (OGIB) is not known. Aim of the study was to prospectively evaluate the diagnostic yield of CTA versus DSA for the diagnosis of major OGIB. Material and methods: The institutional review board approved the study and informed consent was obtained from each patient. Patients with major OGIB were prospectively enrolled to undergo both CTA and DSA. Two blinded radiologists each reviewed the CTA and DSA images retrospectively and independently. Contrast material extravasation into the gastrointestinal lumen was considered diagnostic for active bleeding. Primary end point of the study was the diagnostic yield, defined as the frequency a technique identified an active bleeding or a potential bleeding lesion. The diagnostic yield of CTA and DSA were compared by McNemar's test. Results: 24 consecutive patients (11 men; median age 64 years) were included. CTA and DSA identified an active bleeding or a potential bleeding lesion in 92% (22 of 24 patients; 95% CI 72%-99%) and 29% (7 of 24 patients; 95% CI 12%-49%) of patients, respectively (p < 0.001). CTA and DSA identified an active bleeding in 42% (10 of 24; 95% CI 22%-63%) and 21% (5 of 24; 95% CI 7%-42%) of patients, respectively (p = 0.06). Conclusion: Due to the lower invasiveness and higher diagnostic yield CTA should be favored over DSA for the diagnosis of major OGIB. (C) 2016 Published by Elsevier Ireland Ltd.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ROW HELICAL CT; CAPSULE ENDOSCOPY; MULTIDETECTOR CT; MANAGEMENT; ENTEROGRAPHY; LOCALIZATION; ACCURACY; Gastrointestinal bleeding; Digital substraction angiography; Computed tomography angiography |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:00 |
| Last Modified: | 24 Apr 2019 10:39 |
| URI: | https://pred.uni-regensburg.de/id/eprint/267 |
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