Hitzenbichler, F. and Mohr, A. and Salzberger, B. (2019) Pneumocystis jirovecii pneumonia-an opportunistic infection undergoing change. INTERNIST, 60 (7). pp. 669-677. ISSN 0020-9554, 1432-1289
Full text not available from this repository. (Request a copy)Abstract
Pneumocystis jirovecii pneumonia (PcP) has for many years been reported mostly in human immunodeficiency virus-infected patients. Increasingly, it also affects other immunocompromised patients, e.g. after organ or allogeneic stem cell/bone marrow transplantation, patients with hematologic malignancies or autoimmune diseases. The diagnosis of PcP relies on a critical evaluation of clinical symptoms, risk factors, radiologic features and microbiological tests. High dose cotrimoxazole is the most effective therapeutic option. Rapid initiation is essential, since mortality is especially high in patients admitted to intensive care with respiratory failure. This article reviews the current epidemiology of PcP and highlights the diagnostic and therapeutic options. Recommendations for primary and secondary prophylaxis are summarized.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CARINII-PNEUMONIA; HIV; COLONIZATION; DIAGNOSIS; EFFICACY; THERAPY; LUNGS; PCR; HIV; Organ transplantation; Stem cell transplantation; Immunocompromised host; Autoimmune diseases |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 06 Apr 2020 06:05 |
| Last Modified: | 06 Apr 2020 06:05 |
| URI: | https://pred.uni-regensburg.de/id/eprint/26769 |
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