Angstwurm, K. and Neumann, B. (2019) Infections of the central nervous system in immunodeficiency. INTERNIST, 60 (7). pp. 690-700. ISSN 0020-9554, 1432-1289
Full text not available from this repository. (Request a copy)Abstract
Treatments in oncology, transplantation medicine and immunology frequently lead to immunodeficiency. This review presents the most important opportunistic neurologic infections, mostly of the central nervous system (CNS). Signs and symptoms, diagnostic procedures and therapeutic options are presented. The most frequent infections are due to varicella zoster virus (VZV), Cryptococcus neoformans and Toxoplasma gondii; JC virus (JCV) and cytomegalovirus (CMV) are rare causes of encephalitis. Differential diagnoses include infection by non-opportunistic causatives, therapy associated neurotoxicity, Epstein-Barr virus (EBV) associated CNS lymphoma, recurrence of the malignancy, as well as non-infectious diseases like intracranial bleeding, ischemic stroke, autoimmune diseases and posterior reversible leukencephalopathy syndrome. Treatment of these patients, moreover, needs to consider all previous therapies and to involve aneurologist.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; Opportunistic infections, central nervous system; Varicella zoster virus infection; Cryptococcosis; Toxoplasmosis; Leukencephalopathy, progressive multifocal |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 06 Apr 2020 06:06 |
| Last Modified: | 06 Apr 2020 06:06 |
| URI: | https://pred.uni-regensburg.de/id/eprint/26770 |
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