Goldfuss, Sophia and Wittmann, Sigrid and Wuerschinger, Fabian and Bitzinger, Diane and Seyfried, Timo and Holzamer, Andreas and Fischer, Marcus and Camboni, Daniele and Sinner, Barbara and Zausig, York Alexander (2019) Anaesthesia-related complications and side-effects in TAVI: a retrospective study in Germany. BMJ OPEN, 9 (4): e025825. ISSN 2044-6055,
Full text not available from this repository. (Request a copy)Abstract
Objectives This study was performed to analyse anaesthesia-related complications and side effects in patients undergoing transcatheter aortic valve implantation (TAVI) under general anaesthesia. Design Retrospective study. Setting The study was performed as a single-centre study in a hospital of tertiary care in Germany. Participants All 853 patients, who underwent TAVI at the Universitatsklinikum Regensburg between January 2009 and July 2015, were included. 52.5% were female patients. Primary and secondary outcome measures We gathered information, such as recent illness, vital parameters and medication administered during the intervention and postoperatively for 12 hours. We analysed all anaesthesia-related complications and anaesthesia-related side effects that occurred during the intervention and entire hospital stay. Results We analysed all 853 TAVI procedures. The mean patient age was 79 +/- 6 years. In 99.5% of cases, we used volatile-based anaesthesia. 2.8% (n=24; transfemoral (TF): n=19 [3.8%]; transapical (TA): n=5 [1.4%]) of all cases suffered from anaesthesia-related complications. 819 (TF: n=447; TA: n=372) anaesthesia-related side effects occurred in 586 (68.7%, TF: n=325 [64.2%], TA: n=261 [75.2%]) patients. Neither the complications nor the side effects had any serious consequences. Intraoperative hypothermia in 44% of cases (TF: n=202 [39.9%]; TA: n=173 [49.9%]) and postoperative nausea and vomiting in 27% (n=232; TF: n=131 [25.9%], TA: n=101 [29.1%]) of cases were the most common anaesthesia-related side effects. Conclusion In this study, serious anaesthesia-related complications were rarely seen, and non-critical anaesthesia-related side effects could have been avoided through consistent prophylaxis and management. Therefore, despite their high anaesthetic risk, general anaesthesia is justifiable in patients who underwent TAVI.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | AORTIC-VALVE IMPLANTATION; RISK-FACTORS; POSTOPERATIVE DELIRIUM; GENERAL-ANESTHESIA; LOCAL-ANESTHESIA; NAUSEA; PREVENTION; MORBIDITY; MORTALITY; OUTCOMES; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Apr 2020 07:25 |
| Last Modified: | 14 Apr 2020 07:25 |
| URI: | https://pred.uni-regensburg.de/id/eprint/26909 |
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