Interplay of Na+ Balance and Immunobiology of Dendritic Cells

Neubert, Patrick and Schroeder, Agnes and Mueller, Dominik N. and Jantsch, Jonathan (2019) Interplay of Na+ Balance and Immunobiology of Dendritic Cells. FRONTIERS IN IMMUNOLOGY, 10: 599. ISSN 1664-3224

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Abstract

Local Na+ balance emerges as an important factor of tissue microenvironment. On the one hand, immune cells impact on local Na(+ )levels. On the other hand, Na+ availability is able to influence immune responses. In contrast to macrophages, our knowledge of dendritic cells (DCs) in this state of affair is rather limited. Current evidence suggests that the impact of increased Na+ on DCs is context dependent. Moreover, it is conceivable that DC immunobiology might also be influenced by Na+-rich-diet-induced changes of the gut microbiome.

Item Type: Article
Uncontrolled Keywords: GROWTH-FACTOR-C; INFLAMMATORY RESPONSE; IMMUNE CELLS; DIETARY SALT; I INTERFERON; SKIN SODIUM; MACROPHAGES; ACTIVATION; STORAGE; TISSUE; dendritic cells; Na+ balance; antigen-presentation; Nfat5; kidney; skin microenvironment
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Kieferorthopädie
Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Depositing User: Petra Gürster
Date Deposited: 27 Mar 2020 10:59
Last Modified: 27 Mar 2020 10:59
URI: https://pred.uni-regensburg.de/id/eprint/27326

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