Pantziarka, Pan and Ghibelli, Lina and Reichle, Albrecht (2019) A Computational Model of Tumor Growth and Anakoinosis. FRONTIERS IN PHARMACOLOGY, 10: 287. ISSN 1663-9812,
Full text not available from this repository. (Request a copy)Abstract
Anakoinosis is a new cancer treatment paradigm that posits a key role for communicative reprogramming within tumor systems. To date no mathematical or computational models of anakoinosis have been developed. Here we outline the NEATG_A system, a first computational model of communicative reprogramming. The model recapitulates key features of real tumor systems and responses to both traditional cytotoxic treatments and biomodulatory/anakoinotic treatments. Results are presented and discussed, particularly with respect to the implications for future cancer treatment protocols.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CANCER; EVOLUTION; APOPTOSIS; BIOLOGY; SYSTEMS; anakoinosis; computational model; cancer; drug repurposing; biomodulatory therapy |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 Apr 2020 07:15 |
| Last Modified: | 20 Apr 2020 07:15 |
| URI: | https://pred.uni-regensburg.de/id/eprint/27336 |
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