Verloh, Niklas and Jensch, Isabel and Luerken, Lukas and Haimerl, Michael and Dollinger, Marco and Renner, Philipp and Wiggermann, Philipp and Werner, Jens Martin and Zeman, Florian and Stroszczynski, Christian and Beyer, Lukas Philipp (2019) Similar complication rates for irreversible electroporation and thermal ablation in patients with hepatocellular tumors. RADIOLOGY AND ONCOLOGY, 53 (1). pp. 116-122. ISSN 1318-2099, 1581-3207
Full text not available from this repository. (Request a copy)Abstract
Background. To compare the frequency of adverse events of thermal microwave (MWA) and radiofrequency ablation (RFA) with non-thermal irreversible electroporation (IRE) in percutaneous ablation of hepatocellular carcinoma (HCC). Patients and methods. We retrospectively analyzed 117 MWA/RFA and 47 IRE procedures (one tumor treated per procedure; 144 men and 20 women; median age, 66 years) regarding adverse events, duration of hospital and intensive care unit (ICU) stays and occurrence of a post-ablation syndrome. Complications were classified according to the Clavien & Dindo classification system. Results. 70.1% of the RFA/MWA and 63.8% of the IRE procedures were performed without complications. Grade I and II complications (any deviation from the normal postinterventional course, e.g., analgesics) occurred in 26.5% (31/117) of MWA/RFA and 34.0% (16/47) of IRE procedures. Grade III and IV (major) complications occurred in 2.6% (3/117) of MWA/RFA and 2.1% (1/47) of IRE procedures. There was no significant difference in the frequency of complications (p = 0.864), duration of hospital and ICU stay and the occurrence of a post-ablation syndrome between the two groups. Conclusions. Our results suggest that thermal (MWA and RFA) and non-thermal IRE ablation of malignant liver tumors have comparable complication rates despite the higher number of punctures and the lack of track cauterization in IRE.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MALIGNANT LIVER-TUMORS; PERCUTANEOUS RADIOFREQUENCY ABLATION; TISSUE ABLATION; MICROWAVE ABLATION; HEPATIC-TUMORS; BLOOD-FLOW; CARCINOMA; EFFICACY; SAFETY; MANAGEMENT; tumor ablation; interventional oncology; complications; adverse events; RFA; MWA; IRE |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie Medicine > Lehrstuhl für Röntgendiagnostik Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 16 Apr 2020 12:24 |
| Last Modified: | 16 Apr 2020 12:24 |
| URI: | https://pred.uni-regensburg.de/id/eprint/27495 |
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