Pellegrini, Costanza and Husser, Oliver and Kim, Won-Keun and Holzamer, Andreas and Walther, Thomas and Rheude, Tobias and Mayr, Nicola Patrick and Trenkwalder, Teresa and Joner, Michael and Michel, Jonathan and Chaustre, Fabian and Kastrati, Adnan and Schunkert, Heribert and Burgdorf, Christof and Hilker, Michael and Moellmann, Helge and Hengstenberg, Christian (2019) Predictors of Need for Permanent Pacemaker Implantation and Conduction Abnormalities With a Novel Self-expanding Transcatheter Heart Valve. REVISTA ESPANOLA DE CARDIOLOGIA, 72 (2). pp. 145-153. ISSN 0300-8932, 1579-2242
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Introduction and objectives: The incidence of permanent pacemaker implantation (PPI) and new conduction abnormalities (CA) with the ACURATE neo (Symetis S.A., Eclubens, Switzerland) has not been studied in detail. We aimed to analyze their predictors, evaluating patient- and device-related factors, including implantation depth and device-to-annulus ratio (DAR). Methods: Two analyses of a multicenter population were performed: new PPI in pacemaker-naive patients (n = 283), and PPI/new-CA in patients without prior CA or pacemaker (n = 232). Results: A new PPI was required in 9.9% of patients, who had a higher body mass index, higher rate of right bundle branch block and bradycardia. Neither implantation depth nor DAR differed in patients with PPI compared with those without. In the multivariable analysis neither DAR (OR, 1.010; 95%CI, 0.967-1.055; P = .7) nor implantation depth (OR, 0.972; 95%CI, 0.743-1.272; P = .8) predicted PPI. Only high body mass index, bradycardia and right bundle branch block persisted as independent predictors. PPI/ new-onset CA occurred in 22.8% of patients and was associated with a higher logistic EuroSCORE. Neither implantation depth nor DAR differed in patients with PPI/new-CA vs those without (7.3 +/- 1.9 vs 7.1 +/- 1.5 mm; P = .6 and 41.0 +/- 7.9 vs 42.2 +/- 10.1%; P = .4). The only predictor of PPI/new-CA was a higher logistic EuroSCORE (OR, 1.039; 95%CI, [1.008-1.071]; P = .013). Conclusions: New PPI and new-onset CA rates were low with the ACURATE neo. These were mainly influenced by patient characteristics and not by device-depending factors. (C) 2018 Sociedad Espanola de Cardiologia. Published by Elsevier Espana, S.L.U. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BUNDLE-BRANCH BLOCK; AORTIC-VALVE; SAPIEN 3; CONSENSUS DOCUMENT; CLINICAL-OUTCOMES; REPLACEMENT; GENERATION; EXPERIENCE; SYSTEM; DEPTH; Transcatheter aortic valve implantation; Conduction abnormalities; Permanent pacemaker implantation; Predictors |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 Apr 2020 05:06 |
| Last Modified: | 20 Apr 2020 05:06 |
| URI: | https://pred.uni-regensburg.de/id/eprint/27600 |
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