Kuipers, J. G. and Koller, M. and Zeman, F. and Mueller, K. and Rueffer, J. U. (2019) Adherence and health literacy as related to outcome of patients treated for rheumatoid arthritis: Analyses of a large-scale observational study. ZEITSCHRIFT FUR RHEUMATOLOGIE, 78 (1). pp. 74-81. ISSN 0340-1855, 1435-1250
Full text not available from this repository. (Request a copy)Abstract
BackgroundDisabilities in daily living and quality of life are key endpoints for evaluating the treatment outcome for rheumatoid arthritis (RA). Factors possibly contributing to good outcome are adherence and health literacy.MethodsThe survey included arepresentative nationwide sample of German rheumatologists and their patients with RA. The physician questionnaire included the disease activity score (DAS28) and medical prescriptions. The patient questionnaire included fatigue (EORTC QLQ-FA13), health assessment questionnaire (HAQ), quality of life (SF-12), health literacy (HELP), and patients' listings of their medications. Adherence was operationalized as follows: patient-reported (CQR5), behavioral (concordance between physicians' and patients' listings of medications), physician-assessed, and acombined measure of physician rating (1=very adherent, 0=less adherent) and the match between physicians' prescriptions and patients' accounts of their medications (1=perfect match, 0=no perfect match) that yielded three categories of adherence: high, medium, and low. Simple and multiple linear regressions (controlling for age, sex, smoking, drinking alcohol, and sport) were calculated using adherence and health literacy as predictor variables, and disease activity and patient-reported outcomes as dependent variables.Results708 pairs of patient and physician questionnaires were analyzed. The mean patient age (73% women) was 60years (SD=12). Multiple regression analyses showed that high adherence was significantly associated with 5/7 outcome variables and health literacy with 7/7 outcome variables.ConclusionAdherence and health literacy had weak but consistent effects on most outcomes. Thus, enhancing adherence and understanding of medical information could improve outcome, which should be investigated in future interventional studies.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MEDICATION ADHERENCE; QUESTIONNAIRE; DIVERSE; VERSION; Rheumatoid arthritis; Therapy; Adherence |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 Apr 2020 06:53 |
| Last Modified: | 20 Apr 2020 06:53 |
| URI: | https://pred.uni-regensburg.de/id/eprint/27661 |
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