Caputo, Mahrrouz and Horn, Johannes and Karch, Andre and Akmatov, Manas K. and Becher, Heiko and Braun, Bettina and Brenner, Hermann and Castell, Stefanie and Fischer, Beate and Giani, Guido and Guenther, Kathrin and Hoffmann, Barbara and Joeckel, Karl-Heinz and Keil, Thomas and Klueppelholz, Birgit and Krist, Lilian and Leitzmann, Michael F. and Lieb, Wolfgang and Linseisen, Jakob and Meisinger, Christa and Moebus, Susanne and Obi, Nadia and Pischon, Tobias and Schipf, Sabine and Schmidt, Boerge and Sievers, Claudia and Steinbrecher, Astrid and Voelzke, Henry and Mikolajczyk, Rafael (2019) Herpes zoster incidence in Germany - an indirect validation study for self-reported disease data from pretest studies of the population-based German National Cohort. BMC INFECTIOUS DISEASES, 19: 99. ISSN 1471-2334,
Full text not available from this repository. (Request a copy)Abstract
BackgroundUntil now, herpes zoster (HZ)-related disease burden in Germany has been estimated based on health insurance data and clinical findings. However, the validity of self-reported HZ is unclear. This study investigated the validity of self-reported herpes zoster (HZ) and its complication postherpetic neuralgia (PHN) using data from the pretest studies of the German National Cohort (GNC) in comparison with estimates based on health insurance data.MethodsData of 4751 participants aged between 20 and 69years from two pretest studies of the GNC carried out in 2011 and 2012 were used. Based on self-reports of physician-diagnosed HZ and PHN, age- and sex-specific HZ incidence rates and PHN proportions were estimated. For comparison, estimates based on statutory health insurance data from the German population were considered.ResultsEleven percent (95%-CI, 10.4 to 12.3, n=539) of the participants reported at least one HZ episode in their lifetime. Our estimated age-specific HZ incidence rates were lower than previous estimates based on statutory health insurance data. The PHN proportion in participants older than 50years was 5.9% (1.9 to 13.9%), which was in line with estimates based on health insurance data.ConclusionAs age- and sex-specific patterns were comparable with that in health insurance data, self-reported diagnosis of HZ seems to be a valid instrument for overall disease trends. Possible reasons for observed differences in incidence rates are recall bias in self-reported data or overestimation in health insurance data.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | POSTHERPETIC NEURALGIA; MYOCARDIAL-INFARCTION; AGREEMENT; HYPERTENSION; VALIDITY; STROKE; QUESTIONNAIRE; RECORDS; German National Cohort; Incidence; Self-reports; Validity; Herpes zoster; Postherpetic neuralgia |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Institut für Epidemiologie und Präventivmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 27 Apr 2020 06:31 |
| Last Modified: | 27 Apr 2020 06:31 |
| URI: | https://pred.uni-regensburg.de/id/eprint/27693 |
Actions (login required)
 |
View Item |
