Niessen, C. and Beyer, L. P. and Haimerl, M. and Schicho, A. and Stroszczynski, C. and Wiggermann, P. and Jung, E. M. (2019) Percutaneous irreversible electroporation of hepatocellular carcinoma: Contrast-enhanced ultrasound-findings during 1-year follow-up. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 72 (1). pp. 85-93. ISSN 1386-0291, 1875-8622
Full text not available from this repository. (Request a copy)Abstract
PURPOSE: To assess the postprocedure findings after percutaneous irreversible electroporation (IRE) of hepatocellular carcinoma (HCC) in contrast-enhanced ultrasound (CEUS). MATERIALS AND METHODS: Percutaneous IRE was performed in a total of 22 patients with 24 HCC tumours following interdisciplinary tumour board review. The lesions were documented using CEUS before, immediately and within 24 hours after IRE. During follow-up CEUS was performed at 6 weeks and 3, 9, and 12 months after ablation. Two experienced radiologists evaluated the acquired CEUS image date in a consensus reading. RESULTS: Median tumour size before treatment was 13.7 +/- 4.8 mm (short axis) and 16.0 +/- 5.2 mm (long axis). All HCC lesions showed arterial hyperenhancement in CEUS. Median size of the ablation defect after ablation was 29.3 +/- 5.2 mm (short axis) and 31.6 +/- 5.6 mm (long axis). After IRE all tumours showed complete devascularization. The size of the ablation defects showed significant shrinkage and reduced peripheral enhancement in the course of follow-up. At 12 months follow-up the ablation defect size decreased to 16.7 +/- 4.3 mm (short axis) and 18.3 +/- 4.1 mm (long axis). CONCLUSION: CEUS showed a complete devascularization of HCC tumours after IRE. Post-intervetional peripheral enhancement returned to normal during follow-up and may represent zones of reversible damage of cellular integrity through electroporation. A significant shrinkage of the ablation defects during 12 month of follow-up was seen in all cases.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HEPATIC MALIGNANT-TUMORS; RADIOFREQUENCY ABLATION; SAFETY; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 21 Apr 2020 06:51 |
| Last Modified: | 21 Apr 2020 06:51 |
| URI: | https://pred.uni-regensburg.de/id/eprint/27787 |
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