Deterioration rates in Virtual Reality Therapy: An individual patient data level meta-analysis

Fernandez-Alvarez, Javier and Rozental, Alexander and Carlbring, Per and Colombo, Desiree and Riva, Giuseppe and Anderson, Page L. and Maria Banos, Rosa and Benbow, Amanda A. and Bouchard, Stephane and Maria Breton-Lopez, Juana and Cardenas, Georgina and Difede, JoAnn and Emmelkamp, Paul and Garcia-Palacios, Azucena and Guillen, Veronica and Hoffman, Hunter and Kampann, Isabel and Moldovan, Ramona and Muehlberger, Andreas and North, Max and Pauli, Paul and Castro, Wenceslao Penate and Quero, Soledad and Tortella-Feliu, Miguel and Wyka, Kataryzna and Botella, Cristina (2019) Deterioration rates in Virtual Reality Therapy: An individual patient data level meta-analysis. JOURNAL OF ANXIETY DISORDERS, 61. pp. 3-17. ISSN 0887-6185, 1873-7897

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Abstract

Ample evidence supports the use of Virtual Reality (VR) for anxiety disorders. Nonetheless, currently there is no evidence about moderators or potential negative effects of VR treatment strategies. An Individual Patient Data (IPD) approach was employed with 15 retrieved datasets. The current study sample was composed of 810 patients. Randomized control trials (RCTs) for each primary outcome measure were performed, in addition to moderator analyses of the socio-demographic variables. Deterioration rates were 14 patients (4.0%) in VR, 8 (2.8%) in active control conditions, and 27 (15%) in the WL condition. With regard to receiving treatment, patients in a waiting list control condition had greater odds of deteriorating than in the two active conditions, odds ratios (ORs) 4.87, 95% confidence interval (CI) [0.05, 0.671. In the case of the socio-demographic variables, none of them were associated with higher or lower odds of deterioration, with the exception of marital status in the WL condition; married people presented a significantly lower probability of deterioration, OR 0.19, 95% CI [0.05, 0.67]. Finally, when comparing pooled effects of VR versus all control conditions, the OR was 0.61 (95% CI 0.31-1.23) in favor of VR, although this result was not statistically significant. This study provides evidence about the deterioration rates of a therapeutic VR approach, showing that the number of deteriorated patients coincides with other therapeutic approaches, and that deterioration is less likely to occur, compared to patients in WL control groups.

Item Type: Article
Uncontrolled Keywords: IN-VIVO EXPOSURE; POSTTRAUMATIC-STRESS-DISORDER; COGNITIVE-BEHAVIOR THERAPY; SOCIAL ANXIETY DISORDER; ONE-SESSION TREATMENT; GRADED EXPOSURE; PANIC DISORDER; PSYCHOLOGICAL TREATMENTS; MENTAL-HEALTH; SUDDEN GAINS; Virtual reality; Anxiety disorders; Deterioration rates; Individual patient data analysis
Subjects: 100 Philosophy & psychology > 150 Psychology
Divisions: Human Sciences > Institut für Psychologie
Human Sciences > Institut für Psychologie > Lehrstuhl für Klinische Psychologie und Psychotherapie - Lehrstuhl für Psychologie VIII - Prof. Dr. Andreas Mühlberger
Depositing User: Dr. Gernot Deinzer
Date Deposited: 22 Apr 2020 06:15
Last Modified: 22 Apr 2020 06:15
URI: https://pred.uni-regensburg.de/id/eprint/27877

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