Recommendations for ototoxicity surveillance for childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCare Consortium

Clemens, Eva and van den Heuvel-Eibrink, Marry M. and Mulder, Renee L. and Kremer, Leontien C. M. and Hudson, Melissa M. and Skinner, Roderick and Constine, Louis S. and Bass, Johnnie K. and Kuehni, Claudia E. and Langer, Thorsten and van Dalen, Elvira C. and Bardi, Edith and Bonne, Nicolas-Xavier and Brock, Penelope R. and Brooks, Beth and Carleton, Bruce and Caron, Eric and Chang, Kay W. and Johnston, Karen and Knight, Kristin and Nathan, Paul C. and Orgel, Etan and Prasad, Pinki K. and Rottenberg, Jan and Scheinemann, Katrin and de Vries, Andrica C. H. and Walwyn, Thomas and Weiss, Annette and Zehnhoff-Dinnesen, Antoinette Am and Cohn, Richard J. and Landier, Wendy and Kadan-Lottick, Nina and Levitt, Gill and Hoetink, Alex and Mussman, John (2019) Recommendations for ototoxicity surveillance for childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCare Consortium. LANCET ONCOLOGY, 20 (1). E29-E41. ISSN 1470-2045, 1474-5488

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Abstract

Childhood, adolescent, and young adult (CAYA) cancer survivors treated with platinum-based drugs, head or brain radiotherapy, or both have an increased risk of ototoxicity (hearing loss, tinnitus, or both). To ensure optimal care and reduce consequent problems-such as speech and language, social-emotional development, and learning difficulties-for these CAYA cancer survivors, clinical practice guidelines for monitoring ototoxicity are essential. The implementation of surveillance across clinical settings is hindered by differences in definitions of hearing loss, recommendations for surveillance modalities, and remediation. To address these deficiencies, the International Guideline Harmonization Group organised an international multidisciplinary panel, including 32 experts from ten countries, to evaluate the quality of evidence for ototoxicity following platinum-based chemotherapy and head or brain radiotherapy, and formulate and harmonise ototoxicity surveillance recommendations for CAYA cancer survivors.

Item Type: Article
Uncontrolled Keywords: CISPLATIN-INDUCED OTOTOXICITY; PLATINUM-INDUCED OTOTOXICITY; INDUCED HEARING-LOSS; TERM-FOLLOW-UP; CEREBROSPINAL-FLUID; BRAIN-TUMORS; SODIUM THIOSULFATE; PEDIATRIC-PATIENTS; SHUNT PLACEMENT; GRADING SCALES;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Institut für Epidemiologie und Präventivmedizin
Depositing User: Petra Gürster
Date Deposited: 26 Mar 2020 07:08
Last Modified: 26 Mar 2020 07:08
URI: https://pred.uni-regensburg.de/id/eprint/27925

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