Kuphal, Silke and Bosserhoff, Anja (2009) Recent progress in understanding the pathology of malignant melanoma. JOURNAL OF PATHOLOGY, 219 (4). pp. 400-409. ISSN 0022-3417, 1096-9896
Full text not available from this repository. (Request a copy)Abstract
Recently, several important findings on melanoma development and progression have accelerated progress towards a molecular understanding of melanoma biology. Furthermore, the development of experimental tools, such as a wide range of cell lines and animal models of metastasis, has turned melanoma into a model for general tumour research. However, it has also become evident that melanoma is distinct from other tumours with regard to its cellular origin and pathophysiological mechanisms. This review focuses on important new findings that have contributed to a greater understanding of the molecular processes leading to melanoma. Translating these innovative new results into potent therapeutic approaches will require even more effort. Copyright (C) 2009 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | FIBROBLAST-GROWTH-FACTOR; NEVUS-CELL NEVUS; BETA-CATENIN; METASTATIC MELANOMA; NEURAL CREST; MELANOCYTIC LESIONS; CANCER-CELLS; FACTOR RNA; IN-VIVO; EXPRESSION; melanoma; ephrinA2; FGFR2; PTEN; BRAF; TGF-beta; p16(INK4A); p14(ARF); IGFBP7; p53; stem cell marker; ABCB5; Nodal; Snail; CYLD; MITF; mesenchymal-elongated-type and rounded-amoeboid mode of movement; LKB1; AMPK |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Pathologie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 29 Nov 2022 07:54 |
| Last Modified: | 29 Nov 2022 07:54 |
| URI: | https://pred.uni-regensburg.de/id/eprint/28061 |
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