Korsun, P. and Bals-Pratsch, M. and Ortmann, O. and Markus, S. and Germer, U. (2016) Antenatal Diagnosis of Dizygotic, Monochorionic Twins Following IVFI/CSI Pranatale Diagnose von dizygoten, monochorialen Gemini. GEBURTSHILFE UND FRAUENHEILKUNDE, 76 (6). pp. 727-730. ISSN 0016-5751, 1438-8804
Full text not available from this repository. (Request a copy)Abstract
Monochorionic twins are usually monozygotic and thus usually have the same sex. A case of monochorionic diamniotic twins following IVF/ ICSI and laser treatment of the zona pellucida ("assisted hatching") is presented in which partial embryo amalgamation appears to have occurred. Discordant sex between the twins was suspected on detailed antenatal ultrasound at 13 + 3 weeks gestation and was confirmed on subsequent examinations. The sexual phenotype at birth was female for one twin and male for the other. Placental histology confirmed the monochorionic, diamniotic situation. Cytogenetic analysis of both twins was carried out postpartum on various tissues. On karyotyping of blood lymphocytes the male and female twins each had one mosaic of male and female cells. Oral mucosal cells showed normal male and female karyotypes respectively. Analysis of urothelium showed a normal result for the male infant, and a weak gonosomal mosaic with an XX and XY constellation for the female infant. At least for blood lymphocytes, a diagnosis of chimerism was proven.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BLOOD CHIMERISM; TRANSFUSION SYNDROME; DISCORDANT; PREGNANCY; FERTILIZATION; ULTRASOUND; RARE; SEX; sex discordance; gemini; ART; sonography |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Mar 2019 09:14 |
| Last Modified: | 22 Mar 2019 09:14 |
| URI: | https://pred.uni-regensburg.de/id/eprint/2808 |
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