Volk, T. and Graf, B. M. and Gogarten, W. and Kessler, P. and Wulf, H. (2009) Recommendations for the treatment of local anaesthetic toxicity with lipids. ANASTHESIOLOGIE & INTENSIVMEDIZIN, 50. pp. 698-702. ISSN 0170-5334,
Full text not available from this repository. (Request a copy)Abstract
Life-threatening signs of local anaesthetic toxicity, such as a sudden loss of consciousness, with or without tonic-clonic convulsions need to be treated immediately by stopping the injection, securing and maintaining the airway and providing adequate oxygenation. Anticonvulsants are recommended. The cardiovascular status must be assessed. In the event of a cardiac arrest, cardiopulmonary resuscitation in accordance with standard protocols must be initiated without delay. It is important to remember that prolonged resuscitation may be necessary. The use of lipid emulsion and a cardiopulmonary bypass may be considered. If lipid is administered, a bolus dose of 1.5 ml/kg (lipid emulsion 20%) followed by a continuous infusion (0.1-0.5 ml/kg/min for 30-10 minutes, respectively) may be appropriate.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | INDUCED CARDIAC-ARREST; TOTAL PARENTERAL-NUTRITION; CENTRAL-NERVOUS-SYSTEM; BRACHIAL-PLEXUS BLOCK; SUCCESSFUL RESUSCITATION; CARDIOVASCULAR COLLAPSE; BUPIVACAINE OVERDOSE; INDUCED ASYSTOLE; FAT EMULSION; RAT MODEL; Intoxication; Local Anaesthetics; Resuscitation; Seizure |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 02 Sep 2020 06:44 |
| Last Modified: | 02 Sep 2020 06:44 |
| URI: | https://pred.uni-regensburg.de/id/eprint/28163 |
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