Whistance, R. N. and Conroy, T. and Chie, W. and Costantini, A. and Sezer, O. and Koller, M. and Johnson, C. D. and Pilkington, S. A. and Arraras, J. and Ben-Josef, E. and Pullyblank, A. M. and Fayers, P. and Blazeby, J. M. (2009) Clinical and psychometric validation of the EORTC QLQ-CR29 questionnaire module to assess health-related quality of life in patients with colorectal cancer. EUROPEAN JOURNAL OF CANCER, 45 (17). pp. 3017-3026. ISSN 0959-8049, 1879-0852
Full text not available from this repository. (Request a copy)Abstract
This international study aimed to test the measurement properties of the updated European Organisation for Research and Treatment of Cancer (EORTC) questionnaire module for colorectal cancer, the QLQ-CR29. The QLQ-CR29 was administered with the QLQ-C30, core questionnaire, to 351 patients from seven countries. Questionnaire scaling and reliability were established and clinical and psychometric validity examined. Patient acceptability and understanding were assessed with a debriefing questionnaire. Multi-trait scaling analyses and face validity refined the module to four scales assessing urinary frequency, faecal seepage, stool consistency and body image and single items assessing other common problems following treatment for colorectal cancer. Scales distinguished between clinically distinct groups of patients and did not correlate with QLQ-C30 scales, demonstrating construct validity. The QLQ-CR29 scores were reproducible over time in stable health. The EORTC QLQ-CR29 demonstrates sufficient validity and reliability to support its use to supplement the EORTC QLQ-C30 to assess patient-reported outcomes during treatment for colorectal cancer in clinical trials and other settings. (C) 2009 Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | EUROPEAN-ORGANIZATION; RECTAL-CANCER; FUNCTIONAL ASSESSMENT; INSTRUMENT; ONCOLOGY; TRIALS; Questionnaire; Quality of life; Colorectal cancer; EORTC; Validation |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 02 Sep 2020 08:19 |
| Last Modified: | 02 Sep 2020 08:19 |
| URI: | https://pred.uni-regensburg.de/id/eprint/28177 |
Actions (login required)
 |
View Item |
