Ahn, J. and Moore, S. C. and Albanes, D. and Huang, W-Y and Leitzmann, M. F. and Hayes, R. B. (2009) Height and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trial. BRITISH JOURNAL OF CANCER, 101 (3). pp. 522-525. ISSN 0007-0920,
Full text not available from this repository. (Request a copy)Abstract
BACKGROUND: The relationship between prostate cancer and height is uncertain. METHODS: We prospectively examined the association of height with prostate cancer among 34268 men in the prostate, lung, colorectal, and ovarian cancer trial. Anthropometry was assessed at baseline and 2144 incident prostate cancer cases were identified upto 8.9 years of follow-up. RESULTS: Overall, tallness was not associated with the risk of prostate cancer or with the risk of non-aggressive disease, but the risk for aggressive prostate cancer tended to be greater in taller men (Gleason score >> 7 or stage XIII; P trend 0.05; relative risk (RR) for 190 cm + vs << 170 cm = 1.39, 95% confidence interval (95% CI): 0.96-2.01). This association was largely limited to men below the age of 65 years (P trend = 0.008; RR for 190 cm + vs << 170 cm = 1.76, 95% CI: 1.06-2.93; P for interaction = 0.009), although the number of cases was small and risk estimates were somewhat unstable. CONCLUSION: The results of this large prospective prostate cancer screening trial suggest that tallness is associated with increased risk for younger onset aggressive prostate cancer. British Journal of Cancer (2009) 101, 522-525. doi:10.1038/sj.bjc.6605159 www.bjcancer.com Published online 30 June 2009 (C) 2009 Cancer Research UK
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BODY-MASS INDEX; NORWEGIAN MEN; UNITED-STATES; FOLLOW-UP; PHYSICAL-ACTIVITY; SIZE; ANTHROPOMETRY; NUTRITION; COHORTS; WEIGHT; height; prostate cancer; aggressiveness |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Institut für Epidemiologie und Präventivmedizin > Lehrstuhl für Genetische Epidemiologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 10 Sep 2020 13:33 |
| Last Modified: | 10 Sep 2020 13:33 |
| URI: | https://pred.uni-regensburg.de/id/eprint/28727 |
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