Verdonk, Rene and Madry, Henning and Shabshin, Nogah and Dirisamer, Florian and Peretti, Giuseppe M. and Pujol, Nicolas and Spalding, Tim and Verdonk, Peter and Seil, Romain and Condello, Vincenzo and Di Matteo, Berardo and Zellner, Johannes and Angele, Peter (2016) The role of meniscal tissue in joint protection in early osteoarthritis. KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, 24 (6). pp. 1763-1774. ISSN 0942-2056, 1433-7347
Full text not available from this repository. (Request a copy)Abstract
It is widely accepted that partial meniscectomy leads to early onset of osteoarthritis (OA). A strong correlation exists between the amount and location of the resected meniscus and the development of degenerative changes in the knee. On the other hand, osteoarthritic changes of the joint alter the structural and functional integrity of meniscal tissue. These alterations might additionally compromise the limited healing capacity of the meniscus. In young, active patients without cartilage damage, meniscus therapy including partial meniscectomy, meniscus suture, and meniscus replacement has proven beneficial effects in long-term studies. Even in an early osteoarthritic milieu, there is a relevant regenerative potential of the meniscus and the surrounding cartilage. This potential should be taken into account, and meniscal surgery can be performed with the correct timing and the proper indication even in the presence of early OA. Level of evidence IV.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TERM-FOLLOW-UP; MESENCHYMAL STEM-CELLS; ARTHROSCOPIC PARTIAL MENISCECTOMY; CRUCIATE LIGAMENT RECONSTRUCTION; PARTIAL MEDIAL MENISCECTOMY; DISCOID LATERAL MENISCUS; HIGH TIBIAL OSTEOTOMY; POLYURETHANE SCAFFOLD; KNEE OSTEOARTHRITIS; CLINICAL-OUTCOMES; Meniscus; Early OA; Partial meniscectomy; Meniscal repair; Scaffold; Allograft |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Unfallchirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 25 Mar 2019 13:06 |
| Last Modified: | 25 Mar 2019 13:06 |
| URI: | https://pred.uni-regensburg.de/id/eprint/2878 |
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