Hilker, R. and Benecke, R. and Deuschl, G. and Fogel, W. and Kupsch, A. and Schrader, C. and Sixel-Doering, F. and Timmermann, L. and Volkmann, J. and Lange, M. (2009) Deep brain stimulation for Parkinson's disease - Consensus recommendations of the German Deep Brain Stimulation Association. NERVENARZT, 80 (6). 646-+. ISSN 0028-2804, 1433-0407
Full text not available from this repository. (Request a copy)Abstract
Deep brain stimulation (DBS) has been shown to be effective for levodopa-responsive symptoms and tremor in Parkinson's disease (PD). The subthalamic nucleus (STN) is the preferred target for most patients suffering from late stage motor complications of the disorder. STN DBS is superior to best medical treatment concerning the control of motor fluctuations and the increase of on-time without dyskinesias. In contrast to DBS of the internal pallidum (GPi), STN stimulation also permits a reduction of the dopaminergic medication. Long-term data demonstrated sustained effectiveness of STN DBS despite progressive disease. DBS of the thalamic ventral intermediate nucleus (VIM) is an alternative target in older PD patients with severe PD tremor refractory to medication. In order to minimize potential risks and side effects, the use of DBS needs careful adherence to inclusion and exclusion criteria for eligible PD patients. This paper summarizes the current consensus recommendations of the German Deep Brain Stimulation Association for DBS in PD.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SUBTHALAMIC NUCLEUS STIMULATION; UNILATERAL PALLIDAL STIMULATION; CHRONIC BILATERAL STIMULATION; HIGH-FREQUENCY STIMULATION; TERM FOLLOW-UP; THALAMIC-STIMULATION; GLOBUS-PALLIDUS; ELECTRICAL-STIMULATION; PREVIOUS PALLIDOTOMY; MOVEMENT-DISORDERS; Parkinson's disease; Deep brain stimulation; Consensus recommendations |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurochirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Sep 2020 08:32 |
| Last Modified: | 14 Sep 2020 08:32 |
| URI: | https://pred.uni-regensburg.de/id/eprint/28906 |
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